Detection of subclinical cancers by prostate-specific antigen screening in asymptomatic men from high-risk prostate cancer families.

@article{Matikainen1999DetectionOS,
  title={Detection of subclinical cancers by prostate-specific antigen screening in asymptomatic men from high-risk prostate cancer families.},
  author={Mika P. Matikainen and Johanna Schleutker and Pertti M{\"o}rsky and O. P. Kallioniemi and Teuvo L. J. Tammela},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={1999},
  volume={5 6},
  pages={1275-9}
}
Positive family history is a significant risk factor for prostate cancer. Improved knowledge of the epidemiology and molecular basis of hereditary prostate cancer has led to a need for counseling and clinical follow-up for men with a positive family history of prostate cancer. However, very little information is available on the efficacy of early screening procedures, such as serum prostate-specific antigen (PSA) measurements, in the management of genetically predisposed, high-risk individuals… CONTINUE READING