Detection of sputum cofilin-1 as indicator of malignancy

  title={Detection of sputum cofilin-1 as indicator of
  author={M. P. Rangel and Leila Anton{\^a}ngelo and M.M.P. Acencio and C. S. Faria and V. K. de S{\'a} and P. S. Le{\~a}o and Chiraz Farhat and A. T. Fabro and Adhemar Longatto and R. Reis and Tereza Takagaki and V L Capelozzi},
  booktitle={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
Cofilin-1 (CFL1), a small protein of 18 kDa, has been studied as a biomarker due to its involvement in tumor cell migration and invasion. Our aim was to evaluate CFL1 as an indicator of malignancy and aggressiveness in sputum samples. CFL1 was analyzed by ELISA immunoassay in the sputum of 73 lung cancer patients, 13 cancer-free patients, and 6 healthy… CONTINUE READING