Detection of spreading depolarizations in a middle cerebral artery occlusion model in swine

@article{Kentar2020DetectionOS,
  title={Detection of spreading depolarizations in a middle cerebral artery occlusion model in swine},
  author={Modar Kentar and Martina Mann and Felix Sahm and Arturo Olivares-Rivera and Ren{\'a}n S{\'a}nchez-Porras and Roland Zerelles and Oliver W. Sakowitz and Andreas Unterberg and Edgar Santos},
  journal={Acta Neurochirurgica},
  year={2020},
  volume={162},
  pages={581-592}
}
Background The main objective of this study was to generate a hemodynamically stable swine model to detect spreading depolarizations (SDs) using electrocorticography (ECoG) and intrinsic optical signal (IOS) imaging and laser speckle flowmetry (LSF) after a 30-h middle cerebral artery (MCA) occlusion (MCAo) in German Landrace Swine. Methods A total of 21 swine were used. The study comprised a training group (group 1, n = 7), a group that underwent bilateral craniectomy and MCAo (group 2, n = 10… Expand
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