Detection of serum antibodies to hepatitis C virus in 'false-seronegative' blood donors in Oman.

@article{Alnaqy2006DetectionOS,
  title={Detection of serum antibodies to hepatitis C virus in 'false-seronegative' blood donors in Oman.},
  author={Adel Alnaqy and Safia Al-Harthy and Geraldine Z Kaminski and Said Al-Dhahry},
  journal={Medical principles and practice : international journal of the Kuwait University, Health Science Centre},
  year={2006},
  volume={15 2},
  pages={111-3}
}
OBJECTIVE To detect hepatitis C virus (HCV) antibodies in seronegative donors by disruption of the immune complexes (ICs). SUBJECTS AND METHODS HCV antibody detection was carried out on 600 seronegative donors following an IC dissociation assay. Reverse transcription polymerase chain reaction (RT-PCR) was then performed on the positive results. RESULTS Nine of the 600 samples (1.5%) were positive for IC-dissociated HCV antibodies. Of the 9 only 3 antibody-positive samples had detectable HCV… CONTINUE READING

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