Detection of replicating negative-sense RNAs in CaCo-2 cells infected with human astrovirus

@article{Jang2010DetectionOR,
  title={Detection of replicating negative-sense RNAs in CaCo-2 cells infected with human astrovirus},
  author={So Young Jang and Weon Hwa Jeong and Mi Suk Kim and Young M. Lee and Jae In Lee and Gyu Cheol Lee and Soon Young Paik and Gwang Pyo Koh and Jong Min Kim and Chan Hee Lee},
  journal={Archives of Virology},
  year={2010},
  volume={155},
  pages={1383-1389}
}
Human astrovirus (HAstV) is the second most important cause of viral diarrhea and acute gastroenteritis in infants under five. However, determination of the infectivity of clinical isolates is difficult, and the replication cycle of HAstV is not yet fully understood. In this study, it was attempted to detect negative-sense (−)RNAs generated during the replication of RNA viruses. We used clinical isolates of HAstV to infect CaCo-2 cells. Reverse transcription using only a sense primer followed… CONTINUE READING

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Prevalence and characterization of astroviruses in Argentinean children with acute gastroenteritis

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