Detection of protein complexes using a protein ranking algorithm.

@article{Zaki2012DetectionOP,
  title={Detection of protein complexes using a protein ranking algorithm.},
  author={Nazar M. Zaki and Jose Berengueres and Dmitry Efimov},
  journal={Proteins},
  year={2012},
  volume={80 10},
  pages={2459-68}
}
Detecting protein complexes from protein-protein interaction (PPI) network is becoming a difficult challenge in computational biology. There is ample evidence that many disease mechanisms involve protein complexes, and being able to predict these complexes is important to the characterization of the relevant disease for diagnostic and treatment purposes. This article introduces a novel method for detecting protein complexes from PPI by using a protein ranking algorithm (ProRank). ProRank… CONTINUE READING
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