Detection of potential (anti)progestagenic endocrine disruptors using a recombinant human progesterone receptor binding and transactivation assay.

Abstract

The present work describes the identification of (anti)progestin endocrine disrupting chemicals (EDC) using a two step screening system. In the first step a competitive binding assay was developed using recombinant human progesterone receptor (hPR). The tested chemicals were of various classes like insecticides, their metabolites, industrial chemicals and… (More)
DOI: 10.1016/j.mce.2008.08.021

Topics

7 Figures and Tables

Cite this paper

@article{Viswanath2008DetectionOP, title={Detection of potential (anti)progestagenic endocrine disruptors using a recombinant human progesterone receptor binding and transactivation assay.}, author={Gunda Viswanath and Sujata Halder and Gunda Divya and Chandrajeet B Majumder and Partha Roy}, journal={Molecular and cellular endocrinology}, year={2008}, volume={295 1-2}, pages={1-9} }