Detection of polymorphism in the RING3 gene by high-throughput fluorescent SSCP analysis

Abstract

 We describe the use of a high-throughput, fluorescent, polymorphism-detection system, based on single-strand conformation polymorphism to screen for polymorphism in the RING3 gene. This is the first extensive mutation screen of this major histocompatibility complex-linked gene, and the entire coding region and intron-exon junctions were examined by… (More)
DOI: 10.1007/s002510050491

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