Detection of phosphopeptides by localized surface plasma resonance of titania-coated gold nanoparticles immobilized on glass substrates.

@article{Lin2006DetectionOP,
  title={Detection of phosphopeptides by localized surface plasma resonance of titania-coated gold nanoparticles immobilized on glass substrates.},
  author={Hong-Yi Lin and Cheng-Tai Chen and Y. Chen},
  journal={Analytical chemistry},
  year={2006},
  volume={78 19},
  pages={
          6873-8
        }
}
  • Hong-Yi Lin, Cheng-Tai Chen, Y. Chen
  • Published 2006
  • Chemistry, Medicine
  • Analytical chemistry
  • We herein demonstrate a new sensing method for phosphopeptides by localized surface plasmon resonance (LSPR) using titania-coated gold nanoparticles immobilized on the surface of a glass slide as the sensing substrate and using UV-visible spectrophotometry as the detection tool. Titania has been known to be an effective substrate for binding with phosphorylated species. The detection principle is the shift of wavelength of optical absorption due to SPR of the gold nanoparticles induced by… CONTINUE READING
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