Detection of phenolic glycolipid-I antigen and antibody in sera from new and relapsed lepromatous patients treated with various drug regimens.

@article{Cho1991DetectionOP,
  title={Detection of phenolic glycolipid-I antigen and antibody in sera from new and relapsed lepromatous patients treated with various drug regimens.},
  author={Sangnae Cho and Roland V. Cellona and Tranquilino T. Fajardo and Rodolfo M. Abalos and Eduardo C dela Cruz and Gerald P. Walsh and Joo Deuk Kim and Patrick Joseph Brennan},
  journal={International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association},
  year={1991},
  volume={59 1},
  pages={25-31}
}
Since phenolic glycolipid-I (PGL-I) is an unequivocal marker of Mycobacterium leprae, the antigen has been a good candidate for the serodiagnosis and monitoring the effectiveness of leprosy chemotherapy. As an effort to define the kinetics of the PGL-I antigen and its antibodies in leprosy patients, this study was initiated to examine the serum specimens obtained serially from lepromatous patients under chemotherapy trials. PGL-I was detectable in 64 (94.1%) of 68 new lepromatous (bacterial… CONTINUE READING

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