Detection of peptide-MHC class II complexes on the surface of intact cells.

@article{Busch1990DetectionOP,
  title={Detection of peptide-MHC class II complexes on the surface of intact cells.},
  author={Robyn Busch and Jonathan B. Rothbard},
  journal={Journal of immunological methods},
  year={1990},
  volume={134 1},
  pages={1-22}
}
The interaction of peptides with major histocompatibility complex proteins on the surface of cells is required for their recognition by T lymphocytes. Many studies characterizing the formation of peptide-MHC class II complexes have used either assays for T cell responses or for peptide binding to purified class II molecules. Recently, specific peptide-class II interactions have been demonstrated convincingly on the surface of intact cells. The effects of varying peptide and class II structure… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

Similar Papers

Loading similar papers…