Detection of multiple patterns of oscillatory oxygen consumption in single mouse islets of Langerhans.

@article{Jung1999DetectionOM,
  title={Detection of multiple patterns of oscillatory oxygen consumption in single mouse islets of Langerhans.},
  author={Sung Kook Jung and Craig A Aspinwall and Robert T Kennedy},
  journal={Biochemical and biophysical research communications},
  year={1999},
  volume={259 2},
  pages={331-5}
}
A novel oxygen microsensor was used to measure oxygen levels in single mouse islets as a function of glucose concentration. Oxygen consumption of individual islets was 5.99 +/- 1.17, 9.21 +/- 2.15, and 12.22 +/- 2.16 pmol/min at 3, 10, and 20 mM glucose, respectively (mean +/- SEM, n = 10). Consumption of oxygen was islet-size dependent as larger islets consumed more oxygen than smaller islets but smaller islets consumed more oxygen per unit volume than larger islets. Elevating glucose levels… CONTINUE READING

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