Detection of minimal residual disease in a patient having acute myelogenous leukemia with t(16;21)(p11;q22) treated by allogeneic bone marrow transplantation.

@article{Okoshi2001DetectionOM,
  title={Detection of minimal residual disease in a patient having acute myelogenous leukemia with t(16;21)(p11;q22) treated by allogeneic bone marrow transplantation.},
  author={Yasushi Okoshi and Seiichi Shimizu and Hiroshi Kojima and Naoshi Obara and Harumi Yamamoto Mukai and Takuya Komeno and Yuichi Hasegawa and Naoyoshi Mori and Toshiro Nagasawa},
  journal={Acta haematologica},
  year={2001},
  volume={105 1},
  pages={45-8}
}
A 29-year-old woman having acute myelogeneous leukemia-M1 subtype with the chromosomal abnormality t(16;21)(p11;q22) is presented. Complete blood count at onset showed a hemoglobin level of 7.2 g/dl, a platelet count of 48 x 10(9)/l, and a white blood cell count of 161.2 x 10(9)/l with 99% blasts and 1% lymphocytes. Bone marrow aspiration revealed massive proliferation of blasts that were positive for CD13, CD33, CD34, CD56 and myeloperoxidase, and negative for other T-cell, B-cell and… CONTINUE READING