Detection of melanin-like pigments in the dimorphic fungal pathogen Paracoccidioides brasiliensis in vitro and during infection.

@article{Gmez2001DetectionOM,
  title={Detection of melanin-like pigments in the dimorphic fungal pathogen Paracoccidioides brasiliensis in vitro and during infection.},
  author={Beatriz L G{\'o}mez and Joshua D Nosanchuk and Soraya D{\'i}ez and Sirida Youngchim and Philip Aisen and Luz Elena Cano and {\'A}ngela Restrepo and Arturo Casadevall and Andrew John Hamilton},
  journal={Infection and immunity},
  year={2001},
  volume={69 9},
  pages={5760-7}
}
Melanins are implicated in the pathogenesis of several human diseases, including some microbial infections. In this study, we analyzed whether the conidia and the yeasts of the thermally dimorphic fungal pathogen Paracoccidioides brasiliensis produce melanin or melanin-like compounds in vitro and during infection. Growth of P. brasiliensis mycelia on water… CONTINUE READING