Detection of magnetic nanoparticles in tissue using magneto-motive ultrasound.

@article{Oh2006DetectionOM,
  title={Detection of magnetic nanoparticles in tissue using magneto-motive ultrasound.},
  author={Junghwan Oh and Marc D. Feldman and Jeehyun Kim and Chris Condit and S. N. Emelianov and Thomas E. Milner},
  journal={Nanotechnology},
  year={2006},
  volume={17 16},
  pages={4183-90}
}
The purpose of this study was to demonstrate the magneto-motive ultrasonic detection of superparamagnetic iron oxide (SPIO) nanoparticles as a marker of macrophage recruitment in tissue. The capability of ultrasound to detect SPIO nanoparticles (core diameter ∼20 nm) taken up by murine liver macrophages was investigated. Eight mice were sacrificed two days after the intravenous administration of four SPIO doses (1.5, 1.0, 0.5, and 0.1 mmol Fe/kg body weight). In the iron-laden livers… CONTINUE READING

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