Detection of low level histamine H3 receptor occupancy by autoradiography.


Histamine H(3) receptor antagonists have been proposed as a novel approach to the treatment of cognitive, attentional, and sleep disorders. It is apparent that H(3) receptor antagonists produce in vivo effects in preclinical animal models of central diseases across a wide dose range. In order to characterize the relationship between efficacy in the… (More)
DOI: 10.1016/j.jneumeth.2009.09.015


6 Figures and Tables

Cite this paper

@article{Le2009DetectionOL, title={Detection of low level histamine H3 receptor occupancy by autoradiography.}, author={Siyuan Le and J. Paul Finn and Mary E. Larijani and Michael J Marino and Herv{\'e} J. Schaffhauser}, journal={Journal of neuroscience methods}, year={2009}, volume={185 1}, pages={70-5} }