Detection of lipid-induced structural changes of the Marburg virus matrix protein VP40 using hydrogen/deuterium exchange-mass spectrometry

@inproceedings{Wijesinghe2017DetectionOL,
  title={Detection of lipid-induced structural changes of the Marburg virus matrix protein VP40 using hydrogen/deuterium exchange-mass spectrometry},
  author={Kaveesha J. Wijesinghe and Sarah M Urata and Nisha Bhattarai and Edgar Eduard Kooijman and Bernard S Gerstman and Prem P Chapagain and Sheng Li and Robert V. Stahelin},
  booktitle={The Journal of biological chemistry},
  year={2017}
}
Marburg virus (MARV) is a lipid-enveloped virus from the Filoviridae family containing a negative sense RNA genome. One of the seven MARV genes encodes the matrix protein VP40, which forms a matrix layer beneath the plasma membrane inner leaflet to facilitate budding from the host cell. MARV VP40 (mVP40) has been shown to be a dimeric peripheral protein with a broad and flat basic surface that can associate with anionic phospholipids such as phosphatidylserine. Although a number of mVP40… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

References

Publications referenced by this paper.
Showing 1-10 of 43 references

Similar Papers

Loading similar papers…