Detection of lead (II) with a "turn-on" fluorescent biosensor based on energy transfer from CdSe/ZnS quantum dots to graphene oxide.

@article{Li2013DetectionOL,
  title={Detection of lead (II) with a "turn-on" fluorescent biosensor based on energy transfer from CdSe/ZnS quantum dots to graphene oxide.},
  author={Ming Li and Xuejiao Zhou and Shouwu Guo and Nianqiang Wu},
  journal={Biosensors & bioelectronics},
  year={2013},
  volume={43},
  pages={
          69-74
        }
}
Graphene oxide (GO) sheets are mixed with the aptamer-functionalized CdSe/ZnS quantum dots (QDs). Consequently, the aptamer-conjugated QDs bind to the GO sheets to form a GO/aptamer-QD ensemble, which enables the energy transfer from the QDs to the GO sheets, quenching the fluorescence of QDs. The GO/aptamer-QD ensemble assay acts as a "turn-on" fluorescent sensor for Pb(2+) detection. When Pb(2+) ions are present in the assay, the interaction of Pb(2+) with the aptamer induces a conformational… CONTINUE READING
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