Detection of latent variegate porphyria by fluorescence emission spectroscopy of plasma.

@article{Long1993DetectionOL,
  title={Detection of latent variegate porphyria by fluorescence emission spectroscopy of plasma.},
  author={Colin C Long and Stuart J. Smyth and Jonathan Woolf and Gillian M. Murphy and Andrew Y Finlay and Robert G. Newcombe and George H. Elder},
  journal={The British journal of dermatology},
  year={1993},
  volume={129 1},
  pages={9-13}
}
The plasma of patients with overt variegate porphyria contains porphyrin with a fluorescence emission maximum at about 626 nm, which is diagnostic for the condition. We have evaluated qualitative fluorescence emission scanning of saline-diluted plasma as a method for the identification of asymptomatic carriers of the gene for variegate porphyria. Plasma from 36 unrelated patients with variegate porphyria, 136 of their asymptomatic first- and second-degree relatives aged 15 years or over, and… CONTINUE READING

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