Detection of intrahepatic hepatitis B virus DNA and correlation with hepatic necroinflammation and fibrosis.

@article{Wong2004DetectionOI,
  title={Detection of intrahepatic hepatitis B virus DNA and correlation with hepatic necroinflammation and fibrosis.},
  author={Danny Ka-ho Wong and M. Josephine Yuen and Eric Tse and Hejun Yuan and Simon Siu-Man Sum and Chee-kin Hui and Ching-lung Lai},
  journal={Journal of clinical microbiology},
  year={2004},
  volume={42 9},
  pages={
          3920-4
        }
}
Assessment of intrahepatic hepatitis B virus (HBV) DNA levels in patients with chronic hepatitis B is important in understanding the natural history of the disease and designing antiviral therapy regimens. However, there is no standardized method for the measurement of intrahepatic HBV DNA levels. We describe a convenient novel method for the measurement of intrahepatic HBV DNA levels based on a modified COBAS Amplicor HBV Monitor test for HBV DNA measurement and real-time PCR beta-actin gene… CONTINUE READING
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