Detection of human telomerase reverse transcriptase (hTERT) expression in tissue and pancreatic juice from pancreatic cancer.

@article{Hashimoto2008DetectionOH,
  title={Detection of human telomerase reverse transcriptase (hTERT) expression in tissue and pancreatic juice from pancreatic cancer.},
  author={Yasushi Hashimoto and Yoshiaki Murakami and Kenichiro Uemura and Yasuo Hayashidani and Takeshi Sudo and Hiroki Ohge and Emi Fukuda and Taijiro Sueda and Eiso Hiyama},
  journal={Surgery},
  year={2008},
  volume={143 1},
  pages={
          113-25
        }
}
BACKGROUND Human telomerase reverse transcriptase (hTERT), a catalytic subunit of telomerase, is a promising diagnostic candidate for pancreatic cancer. To evaluate the feasibility of immunohistochemistry (IHC) for the diagnosis of pancreatic cancer, hTERT expression and telomerase activity were assayed in pancreatic tissues, ex vivo brushing, and pancreatic juice samples with various pancreatic diseases. METHODS Telomerase activity was analyzed using the TRAP assay and hTERT was examined by… CONTINUE READING
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