Detection of human polyomavirus 7 in human thymic epithelial tumors.

@article{Rennspiess2015DetectionOH,
  title={Detection of human polyomavirus 7 in human thymic epithelial tumors.},
  author={Dorit Rennspiess and Sreedhar Pujari and Marlies Keijzers and Myrurgia A. Abdul-Hamid and Monique M H Hochstenbag and A. M. Dingemans and Anna Kordelia Kurz and Ernst Jan M. Speel and Anke Maria Haugg and Diana V. Pastrana and Christopher B Buck and Marc H De Baets and Axel zur Hausen},
  journal={Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer},
  year={2015},
  volume={10 2},
  pages={360-6}
}
INTRODUCTION Although the molecular genetics possibly underlying the pathogenesis of human thymoma have been extensively studied, its etiology remains poorly understood. Because murine polyomavirus consistently induces thymomas in mice, we assessed the presence of the novel human polyomavirus 7 (HPyV7) in human thymic epithelial tumors. METHODS HPyV7-DNA Fluorescence in situ hybridization (FISH), DNA-polymerase chain reaction (PCR), and immunohistochemistry (IHC) were performed in 37 thymomas… CONTINUE READING
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