Detection of human papillomavirus DNA and p53 gene mutations in human prostate cancer.

@article{Suzuki1996DetectionOH,
  title={Detection of human papillomavirus DNA and p53 gene mutations in human prostate cancer.},
  author={Hiroaki Suzuki and Akira Komiya and Sara Aida and Haruo Ito and Ryuichi Yatani and Jun Shimazaki},
  journal={The Prostate},
  year={1996},
  volume={28 5},
  pages={318-24}
}
The relationship between integration with human papillomavirus (HPV) and p53 gene mutations in tissues of prostate cancer were examined. Tissue samples analyzed were obtained by total prostatectomy (29 stage B cancer cases) and from autopsy (22 endocrine therapy-resistant metastatic disease cases). HPV DNA was detected in 8 of 51 (16%, 5 in stage B and 3 in autopsy cases) by polymerase chain reaction (PCR) using consensus primers on L1 region. Genotypes of HPV were entirely type 16. Structural… CONTINUE READING
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