Detection of human papillomavirus DNA and p53 codon 72 polymorphism in prostate carcinomas of patients from Argentina

@article{Leirs2005DetectionOH,
  title={Detection of human papillomavirus DNA and p53 codon 72 polymorphism in prostate carcinomas of patients from Argentina},
  author={Gustavo Jos{\'e} Leir{\'o}s and Silvia R Galliano and Mario E Sember and Tomas Kahn and E. Volterra Schwarz and Kumiko Eiguchi},
  journal={BMC Urology},
  year={2005},
  volume={5},
  pages={15 - 15}
}
BACKGROUND Infections with high-risk human papillomaviruses (HPVs), causatively linked to cervical cancer, might also play a role in the development of prostate cancer. Furthermore, the polymorphism at codon 72 (encoding either arginine or proline) of the p53 tumor-suppressor gene is discussed as a possible determinant for cancer risk. The HPV E6 oncoprotein induces degradation of the p53 protein. The aim of this study was to analyse prostate carcinomas and hyperplasias of patients from… CONTINUE READING