Detection of heme oxygenase activity by measurement of CO.

@article{Vreman1999DetectionOH,
  title={Detection of heme oxygenase activity by measurement of CO.},
  author={H. Vreman and David K. Stevenson},
  journal={Current protocols in toxicology},
  year={1999},
  volume={Chapter 9},
  pages={
          Unit 9.2
        }
}
Heme oxygenase (HO) is the first and rate-limiting step in degradation of heme, and in the presence of NADPH-cytochrome P-450 reductase it produces equimolar amounts of biliverdin and CO. CO produced in a closed system can be quantified as described in this unit by gas chromatography as a measure of HO activity in tissue slices, tissue homogenates, and tissue fractions. 
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See above. This paper provides technical details on measuring HO activity by assaying CO production

  • Vreman, Stevenson
  • 1988
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