Detection of generic spaced motifs using submotif pattern mining

@article{Wijaya2007DetectionOG,
  title={Detection of generic spaced motifs using submotif pattern mining},
  author={Edward Wijaya and Kanagasabai Rajaraman and Siu-Ming Yiu and Wing-Kin Sung},
  journal={Bioinformatics},
  year={2007},
  volume={23 12},
  pages={1476-85}
}
MOTIVATION Identification of motifs is one of the critical stages in studying the regulatory interactions of genes. Motifs can have complicated patterns. In particular, spaced motifs, an important class of motifs, consist of several short segments separated by spacers of different lengths. Locating spaced motifs is not trivial. Existing motif-finding algorithms are either designed for monad motifs (short contiguous patterns with some mismatches) or have assumptions on the spacer lengths or can… CONTINUE READING