Detection of gamma-aminobutyric acid (GABA) by longitudinal scalar order difference editing.

@article{Graaf2001DetectionOG,
  title={Detection of gamma-aminobutyric acid (GABA) by longitudinal scalar order difference editing.},
  author={Robin A de Graaf and Douglas L. Rothman},
  journal={Journal of magnetic resonance},
  year={2001},
  volume={152 1},
  pages={124-31}
}
Two novel spectral editing techniques for the in vivo detection of gamma-aminobutyric acid (GABA) are presented. The techniques rely on the generation of longitudinal scalar order (LSO) coherences, which in combination with J-difference editing results in the selective detection of GABA. The utilization of LSO coherences makes the editing sequences insensitive to phase and frequency instabilities. Furthermore, the spectral editing selectivity can be increased independent of the echo time… CONTINUE READING

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