Detection of frequency-dependent endothelial response to oscillatory shear stress using a microfluidic transcellular monitor

Abstract

The endothelial microenvironment is critical in maintaining the health and function of the intimal layer in vasculature. In the context of cardiovascular disease (CVD), the vascular endothelium is the layer of initiation for the progression of atherosclerosis. While laminar blood flows are known to maintain endothelial homeostasis, disturbed flow conditions… (More)
DOI: 10.1038/s41598-017-10636-z

Topics

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