Detection of frequency-dependent endothelial response to oscillatory shear stress using a microfluidic transcellular monitor

@inproceedings{Sei2017DetectionOF,
  title={Detection of frequency-dependent endothelial response to oscillatory shear stress using a microfluidic transcellular monitor},
  author={Yoshitaka J. Sei and Song Ih Ahn and Theodore Virtue and Taeyoung Kim and Yongtae G. Kim},
  booktitle={Scientific Reports},
  year={2017}
}
The endothelial microenvironment is critical in maintaining the health and function of the intimal layer in vasculature. In the context of cardiovascular disease (CVD), the vascular endothelium is the layer of initiation for the progression of atherosclerosis. While laminar blood flows are known to maintain endothelial homeostasis, disturbed flow conditions including those the endothelium experiences in the carotid artery are responsible for determining the fate of CVD progression. We present a… CONTINUE READING