Detection of five novel CTX-M-type extended spectrum beta-lactamases with one to three CTX-M-14 point mutations in isolates from Hefei, Anhui province, China.


Following the introduction of expanded spectrum cephalosporins into clinical usage, the production of extended-spectrum -lactamases (ESBLs) by members of the Enterobacteriaceae has been documented (5, 6). One of these ESBLs, CTX-M, has become the predominant ESBL type in eastern Asia, South America, and Eastern Europe. And it also exhibits an overall… (More)


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