Detection of fentanyl and its analogs by enzyme-linked immunosorbent assay.
@article{Ruangyuttikarn1990DetectionOF, title={Detection of fentanyl and its analogs by enzyme-linked immunosorbent assay.}, author={W. Ruangyuttikarn and M. Y. Law and D. Rollins and D. Moody}, journal={Journal of analytical toxicology}, year={1990}, volume={14 3}, pages={ 160-4 } }
A prototype enzyme-linked immunosorbent assay (ELISA) for fentanyl, a potent synthetic narcotic analgesic, was used to detect the presence of fentanyl and its analogs in human urine. Human drug-free urine was spiked with 0.02 to 100 ng/mL of fentanyl or with 0.1 to 500 ng/mL of each analog and used as a sample in the ELISA. Sensitivity and precision of the assay were analyzed specifically for detection of fentanyl. Cross-reactivities of fentanyl and nine analogs, acetylfentanyl, p… CONTINUE READING
Topics from this paper
53 Citations
An enzyme-linked immunosorbent assay for urinary screening of fentanyl citrate abuse.
- Medicine
- Annals of clinical and laboratory science
- 1995
- 9
- PDF
Development of an enzyme-linked immunosorbent assay for fentanyl and applications of fentanyl antibody-coated nanoparticles for sample preparation.
- Chemistry, Medicine
- Journal of pharmaceutical and biomedical analysis
- 2006
- 13
Rapid quantitative determination of fentanyl in human urine and serum using a gold-based immunochromatographic strip sensor.
- Chemistry, Medicine
- Journal of materials chemistry. B
- 2020
Detectability of fentanyl and designer fentanyls in urine by 3 commercial fentanyl immunoassays.
- Medicine
- Drug testing and analysis
- 2018
- 16
Determination of Fentanyl Analog Exposure Using Dried Blood Spots with LC-MS-MS.
- Medicine
- Journal of analytical toxicology
- 2019
- 10
Cross-reactivity of acetylfentanyl and risperidone with a fentanyl immunoassay.
- Chemistry, Medicine
- Journal of analytical toxicology
- 2014
- 29
- PDF
Quantitative analysis of fentanyl in rat plasma by gas chromatography with nitrogen-phosphorus detection.
- Chemistry, Medicine
- Journal of chromatography. B, Biomedical sciences and applications
- 2001
- 23
A sensitive assay for the simultaneous measurement of alfentanil and fentanyl in plasma.
- Chemistry, Medicine
- Journal of pharmaceutical and biomedical analysis
- 1996
- 20
Application of the fentanyl analog screening kit toward the identification of emerging synthetic opioids in human plasma and urine by LC-QTOF.
- Chemistry, Medicine
- Toxicology letters
- 2019
- 2
Application of a validated UHPLC-MS/MS method for 28 fentanyl-analogue and novel synthetic opioids in whole blood in authentic forensic cases.
- Chemistry, Medicine
- Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
- 2019
- 11
References
SHOWING 1-10 OF 19 REFERENCES
Immunoassay detection of drugs in horses. I. Particle concentration fluoroimmunoassay detection of fentanyl and its congeners.
- Chemistry, Medicine
- Research communications in chemical pathology and pharmacology
- 1987
- 5
High-sensitivity radioimmunoassay screening method for fentanyl.
- Biology, Medicine
- American journal of veterinary research
- 1986
- 16
Identification and quantitative determination of fentanyl metabolites in patients by gas chromatography--mass spectrometry.
- Medicine
- Anesthesiology
- 1984
- 61
Gas chromatographic determination of fentanyl and its analogues in human plasma.
- Chemistry, Medicine
- Journal of analytical toxicology
- 1981
- 68
Immunoassay detection of drugs in racing horses. IV. Detection of fentanyl and its congeners in equine blood and urine by a one step ELISA assay.
- Medicine
- Research communications in chemical pathology and pharmacology
- 1988
- 5
Optimization of the radioimmunoassays for measuring fentanyl and alfentanil in human serum.
- Medicine
- Anesthesiology
- 1984
- 65
Analyzing normetabolites of the fentanyls by gas chromatography/electron capture detection.
- Chemistry, Medicine
- Journal of analytical toxicology
- 1988
- 36
Antibodies to fentanyl.
- Chemistry, Medicine
- The Journal of pharmacology and experimental therapeutics
- 1975
- 33
Opiate receptor interaction of compounds derived from or structurally related to fentanyl.
- Chemistry, Medicine
- Journal of medicinal chemistry
- 1981
- 28
Determination of fentanyl in whole blood at subnanogram concentrations by dual capillary column gas chromatography with nitrogen sensitive detectors and gas chromatography/mass spectrometry.
- Chemistry, Medicine
- Journal of analytical toxicology
- 1988
- 28