Detection of expiratory flow limitation during exercise in COPD patients.

@article{Koulouris1997DetectionOE,
  title={Detection of expiratory flow limitation during exercise in COPD patients.},
  author={N. Koulouris and I. Dimopoulou and P. Valta and R. Finkelstein and M. Cosio and J. Milic-Emili},
  journal={Journal of applied physiology},
  year={1997},
  volume={82 3},
  pages={
          723-31
        }
}
The negative expiratory pressure (NEP) method was used to detect expiratory flow limitation at rest and at different exercise levels in 4 normal subjects and 14 patients with chronic obstructive pulmonary disease (COPD). This method does not require performance of forced expirations, nor does it require use of body plethysmography. It consists in applying negative pressure (-5 cmH2O) at the mouth during early expiration and comparing the flow-volume curve of the ensuing expiration with that of… Expand
Role of inspiratory capacity on exercise tolerance in COPD patients with and without tidal expiratory flow limitation at rest.
TLDR
In patients with flow limitation, inspiratory capacity appears as the best predictor of exercise tolerance, reflecting the presence of dynamic hyperinflation. Expand
Expiratory flow limitation during exercise in COPD: detection by manual compression of the abdominal wall
TLDR
Manual compression of the abdomen during spontaneous expiration is a simple and reliable method for the detection of flow limitation in the chronic obstructive pulmonary disease patients during resting breathing and constant-exercise work is concluded. Expand
Expiratory flow limitation in stable asthmatic patients during resting breathing.
TLDR
Most stable asthmatic patients do not exhibit tidal expiratory flow limitation during resting breathing; and the conventional method for assessing flow limitation may lead to erroneous conclusions. Expand
Methods for Assessing Expiratory Flow Limitation during Tidal Breathing in COPD Patients.
TLDR
Among the currently available techniques, the negative expiratory pressure (NEP) has been validated in a wide variety of settings and disorders and should be regarded as a simple, non invasive, most practical, and accurate new technique. Expand
Methods for Assessing Expiratory Flow Limitation during Tidal Breathing in COPD Patients
TLDR
Among the currently available techniques, the negative expiratory pressure (NEP) has been validated in a wide variety of settings and disorders and should be regarded as a simple, non invasive, most practical, and accurate new technique. Expand
Breathing pattern and gas exchange at peak exercise in COPD patients with and without tidal flow limitation at rest.
TLDR
In chronic obstructive pulmonary disease patients the maximal tidal volume, and hence maximal oxygen consumption, are closely related to the reduced inspiratory capacity. Expand
Flow limitation and dynamic hyperinflation during exercise in COPD patients after single lung transplantation.
TLDR
Most SLT patients for COPD exhibit expiratory flow limitation and dynamic hyperinflation during exercise, whereas maximal dyspnea is variable. Expand
Expiratory flow-limitation and heliox breathing in resting and exercising COPD patients
TLDR
The presence of TEFL has no systematic effects on the respiratory response to heliox, and the heliox-induced decrease of exercise dyspnea is not mainly due to changes in dynamic hyperinflation or TEFL. Expand
Expiratory flow limitation detected by forced oscillation and negative expiratory pressure
TLDR
As forced oscillation technique is automatic and can measure multiple breaths over long periods, it is suitable for monitoring expiratory flow limitation continuously and identifying patients′ breathing close to the onset of expiratories flow limitation, where intermittent sampling may be unrepresentative. Expand
Effect of pulmonary rehabilitation on tidal expiratory flow limitation at rest and during exercise in COPD patients
TLDR
Both NFL and EFL COPD patients improved exercise capacity and patients centered outcomes undergoing the same Pulmonary Rehabilitation (PR) program. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 37 REFERENCES
A simple method to detect expiratory flow limitation during spontaneous breathing.
TLDR
The NEP technique is concluded to provide a simple, rapid, and reliable method for detection of expiratory flow limitation in spontaneously breathing subjects, which does not require the patient's co-operation, and can be applied in different body positions both at rest and during muscular exercise. Expand
Detection of expiratory flow limitation during mechanical ventilation.
TLDR
NEP provides a simple method to detect flow limitation in mechanically ventilated patients and the supine position enhances flow limitation, and the ATM method gave erroneous results in the three non-flow-limited patients. Expand
Ventilatory mechanics and expiratory flow limitation during exercise in patients with obstructive lung disease.
TLDR
Exercise capacity in most subjects was clearly limited by the deranged ventilatory apparatus, and Elevations in mean intrathoracic pressure during exercise also may interfere with venous return and impose an additional limitation. Expand
Expiratory flow limitation and regulation of end-expiratory lung volume during exercise.
TLDR
It is suggested that compression of airways downstream from the flow-limiting segment may elicit a reflex mechanism that influences breathing pattern by terminating expiration prematurely, thus increasing EELV. Expand
Pulmonary mechanics during exercise in subjects with chronic airflow obstruction.
TLDR
In patients with chronic airflow obstruction, little change occurs during exercise in pulmonary mechanics; the tidal flow patterns are dominated by the expired flow-volume curve, which is not changed by exercise; maximum flow occurs in some patients when transpulmonary pressure is still negative. Expand
Relationship between chronic dyspnea and expiratory flow limitation in patients with chronic obstructive pulmonary disease.
TLDR
Expiratory flow limitation as measured by the negative expiratory pressure technique may be more useful in the evaluation of dyspnea in patients with COPD than spirometry measurements. Expand
Effect of mild-to-moderate airflow limitation on exercise capacity.
TLDR
EELV was significantly correlated to both VO2max and FEV1, which suggests a ventilatory influence on exercise capacity; however, the increased EELV and associated pleural pressures could influence cardiovascular function during exercise. Expand
Dependence of maximal flow-volume curves on time course of preceding inspiration in patients with chronic obstruction pulmonary disease.
TLDR
The results imply that the inspiratory maneuver prior to FVC must be standardized, and the dependence of maximal flow-volume curves on the time course of the preceding inspiration is probably related in part to the viscoelastic elements present within the respiratory system. Expand
Flow-volume curves and breathing patterns during exercise in patients with obstructive lung disease.
  • G. Grimby, J. Stiksa
  • Medicine
  • Scandinavian journal of clinical and laboratory investigation
  • 1970
TLDR
Flow-volume curves were recorded in 12 patients with chronic obstructive lung disease at rest, and during forced expiratory vital capacity (MEFV curves) and work, and gas exchange studies during exercise did not explain the limitation of exercise tolerance. Expand
Effect of volume history on successive partial expiratory flow-volume maneuvers.
TLDR
The opposite was observed in this study, which indicates that the increase in Pst(L), which results from parenchymal hysteresis, offsets any dimensional decrease in upstream airways due to airways hysteResis. Expand
...
1
2
3
4
...