Detection of exhaled hydrogen sulphide gas in rats exposed to intravenous sodium sulphide.

@article{Insko2009DetectionOE,
  title={Detection of exhaled hydrogen sulphide gas in rats exposed to intravenous sodium sulphide.},
  author={Michael A Insko and Thomas L. Deckwerth and Paul Hill and Christopher F Toombs and Csaba Szab{\'o}},
  journal={British journal of pharmacology},
  year={2009},
  volume={157 6},
  pages={
          944-51
        }
}
BACKGROUND AND PURPOSE Sodium sulphide (Na(2)S) disassociates to sodium (Na(+)) hydrosulphide, anion (HS(-)) and hydrogen sulphide (H(2)S) in aqueous solutions. Here we have established and characterized a method to detect H(2)S gas in the exhaled breath of rats. EXPERIMENTAL APPROACH Male rats were anaesthetized with ketamine and xylazine, instrumented with intravenous (i.v.) jugular vein catheters, and a tube inserted into the trachea was connected to a pneumotach connected to a H(2)S gas… CONTINUE READING
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