Detection of endogenous iron deposits in the injured mouse spinal cord through high-resolution ex vivo and in vivo MRI.

@article{Blomster2013DetectionOE,
  title={Detection of endogenous iron deposits in the injured mouse spinal cord through high-resolution ex vivo and in vivo MRI.},
  author={Linda V Blomster and Gary J. Cowin and Nyoman D. Kurniawan and Marc J. Ruitenberg},
  journal={NMR in biomedicine},
  year={2013},
  volume={26 2},
  pages={
          141-50
        }
}
The main aim of this study was to employ high-resolution MRI to investigate the spatiotemporal development of pathological features associated with contusive spinal cord injury (SCI) in mice. Experimental mice were subjected to either sham surgery or moderate contusive SCI. A 16.4-T small-animal MR system was employed for nondestructive imaging of post-mortem, fixed spinal cord specimens at the subacute (7 days) and more chronic (28-35 days) stages post-injury. Routine histological techniques… CONTINUE READING
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