Detection of early renal transplant rejection by minimally-invasive monitoring of impedance variability.

@article{Parsonnet2007DetectionOE,
  title={Detection of early renal transplant rejection by minimally-invasive monitoring of impedance variability.},
  author={Victor Parsonnet and Mohamed J Marak and Eric Panken and Mark Jay Zucker and Alexander G. Villanueva and Taras Kucher and Jack Driller and Gabriel Tuder and Ludmilla Olesnicky and William Combs},
  journal={Biosensors & bioelectronics},
  year={2007},
  volume={22 11},
  pages={2749-53}
}
BACKGROUND Allograft rejection that occurs after renal transplants is identified by surveillance biopsies or by abnormal laboratory and/or hemodynamic data. The latter are insensitive markers of rejection that may not appear until significant histologic damage has already occurred. Therefore, a sensitive and specific non-invasive method of detecting early rejection of transplanted solid organs is needed. METHOD A single canine renal allograft was implanted followed by bilateral nephrectomy… CONTINUE READING