Detection of diverse bacterial signatures in atherosclerotic lesions of patients with coronary heart disease.

@article{Ott2006DetectionOD,
  title={Detection of diverse bacterial signatures in atherosclerotic lesions of patients with coronary heart disease.},
  author={Stephan Johannes Ott and Nour Eddine el Mokhtari and Meike Musfeldt and Stephan Hellmig and Sandra Freitag and Ateequr Rehman and Tanja Kuehbacher and Susanna Nikolaus and Pawel Namsolleck and Michael Blaut and Jochen Hampe and Hany Sahly and Alexander Reinecke and Nils Haake and Rainer Guenther and Dietmar Kr{\"u}ger and Markus Lins and Gunhild Herrmann and Ulrich Robert Foelsch and R. N. Simon and Stefan Schreiber},
  journal={Circulation},
  year={2006},
  volume={113 7},
  pages={929-37}
}
BACKGROUND Bacterial infection has been discussed as a potential etiologic factor in the pathophysiology of coronary heart disease (CHD). This study analyzes molecular phylogenies to systematically explore the presence, frequency, and diversity of bacteria in atherosclerotic lesions in patients with CHD. METHODS AND RESULTS We investigated 16S rDNA signatures in atherosclerotic tissue obtained through catheter-based atherectomy of 38 patients with CHD, control material from postmortem… CONTINUE READING
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