Detection of disseminated lung cancer cells in lymph nodes: impact on staging and prognosis.

@article{Passlick1996DetectionOD,
  title={Detection of disseminated lung cancer cells in lymph nodes: impact on staging and prognosis.},
  author={Bernward Passlick and Jakob Robert Izbicki and Boris Kubuschok and O. Thetter and Klaus Pantel},
  journal={The Annals of thoracic surgery},
  year={1996},
  volume={61 1},
  pages={177-82; discussion 183}
}
BACKGROUND A major reason for the high incidence of tumor recurrences in patients with apparently resectable non-small cell lung cancer is presumably early tumor cell dissemination, which is clearly underestimated by current staging procedures. METHODS In this prospective study we assessed the frequency and prognostic significance of early lymphatic tumor cell spread to regional lymph nodes staged as tumor free by conventional histopathology by applying an immunohistochemical assay using… CONTINUE READING

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