• DOI:10.1007/S00216-007-1297-9
Corpus ID: 19256926

Detection of diazepam in urine, hair and preserved oral fluid samples with LC-MS-MS after single and repeated administration of Myolastan® and Valium®

@article{Laloup2007DetectionOD,
  title={Detection of diazepam in urine, hair and preserved oral fluid samples with LC-MS-MS after single and repeated administration of Myolastan® and Valium®},
  author={M. Laloup and Mar{\'i}a del Mar Ram{\'i}rez Fern{\'a}ndez and M. Wood and V. Maes and G. Boeck and Yvan Vanbeckevoort and N. Samyn},
  journal={Analytical and Bioanalytical Chemistry},
  year={2007},
  volume={388},
  pages={1545-1556}
}

M. Laloup, María del Mar Ramírez Fernández, +4 authors N. Samyn

Published 2007

Chemistry, Medicine

Analytical and Bioanalytical Chemistry

Sedative agents are used to facilitate sexual assault due to their ability to render the victim passive, submissive and unable to resist. The primary pharmacological effect of the benzodiazepine tetrazepam is muscle relaxation, whereas the benzodiazepine diazepam acts on the central nervous system (CNS) exerting mainly sedation effects. Therefore, contrary to tetrazepam, diazepam is an often-abused drug, which can potentially be used as a date-rape drug. In this study, we describe the detection… CONTINUE READING

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