Detection of diazepam in urine, hair and preserved oral fluid samples with LC-MS-MS after single and repeated administration of Myolastan® and Valium®

@article{Laloup2007DetectionOD,
  title={Detection of diazepam in urine, hair and preserved oral fluid samples with LC-MS-MS after single and repeated administration of Myolastan{\textregistered} and Valium{\textregistered}},
  author={Marleen Laloup and Mar{\'i}a del Mar Ram{\'i}rez Fern{\'a}ndez and Michelle Wood and Viviane Maes and Gert De Boeck and Yvan Vanbeckevoort and Nele Samyn},
  journal={Analytical and Bioanalytical Chemistry},
  year={2007},
  volume={388},
  pages={1545-1556}
}
Sedative agents are used to facilitate sexual assault due to their ability to render the victim passive, submissive and unable to resist. The primary pharmacological effect of the benzodiazepine tetrazepam is muscle relaxation, whereas the benzodiazepine diazepam acts on the central nervous system (CNS) exerting mainly sedation effects. Therefore, contrary to tetrazepam, diazepam is an often-abused drug, which can potentially be used as a date-rape drug. In this study, we describe the detection… 
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