Detection of convergent and parallel evolution at the amino acid sequence level.

@article{Zhang1997DetectionOC,
  title={Detection of convergent and parallel evolution at the amino acid sequence level.},
  author={Jian Xim Zhang and Shive Kumar},
  journal={Molecular biology and evolution},
  year={1997},
  volume={14 5},
  pages={
          527-36
        }
}
Adaptive evolution at the molecular level can be studied by detecting convergent and parallel evolution at the amino acid sequence level. For a set of homologous protein sequences, the ancestral amino acids at all interior nodes of the phylogenetic tree of the proteins can be statistically inferred. The amino acid sites that have experienced convergent or parallel changes on independent evolutionary lineages can then be identified by comparing the amino acids at the beginning and end of each… CONTINUE READING

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