Detection of colorectal cancer by DNA methylation biomarker SEPT9: past, present and future.

  title={Detection of colorectal cancer by DNA methylation biomarker SEPT9: past, present and future.},
  author={Yuemin Li and Lele Song and Yuan Gong and Baoming He},
  journal={Biomarkers in medicine},
  volume={8 5},
Colorectal cancer has become the third most common cancer in the world. Early diagnosis and treatment can significantly reduce colorectal cancer mortality. The current routinely used fecal-based screening methods do not provide satisfactory sensitivity. Although colonoscopy provides macroscopic diagnosis, the compliance is low due to its inconvenience and complications. Hence, the development of new screening methods is needed urgently. Peripheral blood SEPT9 gene methylation assay has become a… CONTINUE READING
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