Detection of clinically significant, occult prostate cancer metastases in lymph nodes using a splice variant-specific rt-PCR assay for human glandular kallikrein.

@article{Shariat2003DetectionOC,
  title={Detection of clinically significant, occult prostate cancer metastases in lymph nodes using a splice variant-specific rt-PCR assay for human glandular kallikrein.},
  author={Shahrokh F Shariat and Michael W. Kattan and Sibel Erdamar and C. Nguyen and Peter T. Scardino and David M. Spencer and Thomas M. Wheeler and Kevin M. Slawin},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2003},
  volume={21 7},
  pages={1223-31}
}
PURPOSE To compare the detection of human glandular kallikrein 2 (hK2) mRNA expression in archival lymph nodes with disease progression, the development of prostate cancer metastases, and mortality in patients undergoing radical prostatectomy for locally advanced nonmetastatic prostate cancer. PATIENTS AND METHODS We evaluated total RNA extracted from… CONTINUE READING