Detection of circulating tumor lysate–reactive CD4+ T cells in melanoma patients

Abstract

Purpose: We wanted to study whether an allogeneic melanoma lysate would be a feasible stimulatory antigen source for detection of a peripheral CD4+ T-cell immune response in patients with medically untreated malignant melanoma. The lysate was produced from a melanoma cell line (FM3.29) which expresses high amounts of melanoma antigens. Methods: Fresh… (More)
DOI: 10.1007/s00262-004-0502-3

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