Detection of circulating tumor cells in metastatic and clinically localized urothelial carcinoma.

@article{Flaig2011DetectionOC,
  title={Detection of circulating tumor cells in metastatic and clinically localized urothelial carcinoma.},
  author={Thomas Flaig and Shandra Wilson and Adrie Van Bokhoven and Marileila Varella-Garcia and Pamela Wolfe and Paul D. Maroni and Elizabeth Erin Genova and Diana Morales and M. Scott Lucia},
  journal={Urology},
  year={2011},
  volume={78 4},
  pages={863-7}
}
OBJECTIVE To examine the incidence and prognostic value of circulating tumor cells (CTCs) in urothelial cancer (UC). The detection of CTCs is prognostic in several cancer types. METHODS A total of 44 subjects with UC were assessed for CTCs using CellSearch Technology and 7.5 mL of peripheral blood, sorted by magnetic separation (epithelial cell adhesion molecule positive) and immunofluorescent staining (positive for cytokeratin 8, 18, or 19, negative for CD45, positive for 4',6-diamidino-2… CONTINUE READING

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