Detection of chromosome aberrations in paraffin sections of seven gonadal yolk sac tumors of childhood

@article{Jenderny1995DetectionOC,
  title={Detection of chromosome aberrations in paraffin sections of seven gonadal yolk sac tumors of childhood},
  author={Jutta Jenderny and Eckhard K{\"o}ster and Annette Meyer and Olaf Borchers and Werner Grote and Dieter Harms and Ute Jaenig},
  journal={Human Genetics},
  year={1995},
  volume={96},
  pages={644-650}
}
Yolk sac tumors are the most frequent kind of malignant pediatric germ cell tumor and may have a fundamentally different pathogenesis than adult germ cell tumors. Since few cytogenetic studies have been performed so far, in situ hybridization was applied to interphase cell nuclei of seven gonadal yolk sac tumors of childhood in routine paraffin-embedded tissue sections. The panel of chromosome-specific DNA probes was selected on the basis of their relevance in adult germ cell tumors and… CONTINUE READING

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