Detection of chromosomal imbalances in central neurocytomas by using comparative genomic hybridization.

@article{Yin2000DetectionOC,
  title={Detection of chromosomal imbalances in central neurocytomas by using comparative genomic hybridization.},
  author={X-l Yin and Jesse Chung-sean Pang and Angela Bik-Yu Hui and Ho Keung Ng},
  journal={Journal of neurosurgery},
  year={2000},
  volume={93 1},
  pages={77-81}
}
OBJECT Central neurocytomas are rare neuronal tumors commonly found in the intraventricular regions. Little is known about the tumorigenesis of these neoplasms. The aim of this study was to provide an overview of genetic imbalances in central neurocytomas. METHODS In this study, comparative genomic hybridization was used to identify DNA sequence copy number changes (losses and gains) in a series of 10 central neurocytomas. Tumor DNA and normal reference DNA were differentially labeled and… CONTINUE READING

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