Corpus ID: 24000616

Detection of c-myc gene expression in nasopharyngeal carcinoma by nonradioactive in situ hybridization and immunohistochemistry.

  title={Detection of c-myc gene expression in nasopharyngeal carcinoma by nonradioactive in situ hybridization and immunohistochemistry.},
  author={J. Luo and J. Xiao and Z. Tao and X. Li},
  journal={Chinese medical journal},
  volume={110 3},
OBJECTIVE To investigate the c-myc gene expression in nasopharyngeal carcinoma (NPC) at mRNA and protein levels, and to evaluate the relationship between the degree of expression and the clinicopathological data. METHODS The expression of c-myc specific mRNA and protein was detected using in situ hybridization with digoxigenin-labeled probe and immunohistochemistry in 12 cases of normal nasopharyngeal epithelium (NE) and 48 cases of NPC. The intensity of staining for each sample was assessed… Expand
Correlation of chromosomal polysomy with overexpression of c-myc and c-erbB-2 in primary nasopharyngeal carcinoma: Tissue microarray study
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