Detection of c-Sis proto-oncogene transcripts by direct enzyme-labeled cDNA probes and in situ hybridization

@article{Mcclintock2007DetectionOC,
  title={Detection of c-Sis proto-oncogene transcripts by direct enzyme-labeled cDNA probes and in situ hybridization},
  author={J. T. Mcclintock and I J Chan and S R Thaker and Albine Katial and Floyd E. Taub and Amy E. Aotaki-Keen and Leonard M. Hjelmeland},
  journal={In Vitro Cellular \& Developmental Biology - Animal},
  year={2007},
  volume={28},
  pages={102-108}
}
SummaryUsing in situ hybridization and platelet-derived growth factor (PDGF) cDNA probes labeled with horseradish peroxidase, PDGF-A and -B (c-cis proto-oncogene) mRNA transcripts were identified and localized in proliferating cultures. A human retinal pigment epithelial (RPE) cell line and a glial cell line were treated with either transforming growth factor beta-1 (TGFB1), phorbol-12-myristate-13-acetate (PMA), or thrombin from human plasma and compared for their ability to stimulate the… 
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Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: Regulation by TGF‐β
TLDR
It is demonstrated that TGF‐β activated RPE cells produce PDGF that may act on fibroblasts and other mesenchyme derived cells which express PDGF receptors, which may facilitate the formation of fibrovascular tissues associated with PVR.
Tumor Stem Cells: How to Define Them and How to Find Them?
TLDR
This review will summarize the investigated surface markers of haematological and solid tumors’ stem cells since the appropriate identification and isolation of this particular subpopulation of tumor cells will be essential for developing more effective cancer treatments.
Chapter 10 Tumor Stem Cells: How to Define Them and How to Find Them?
TLDR
This review will summarize the investigated surface markers of haematological and solid tumors' stem cells since the appropriate identification and isolation of this particular subpopulation of tumor cells will be essential for developing more effec- tive cancer treatments.
New Technologies and Tissue Repair and Regeneration (2): Other Biotherapeutic Technologies

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