Detection of bacteriophage-infected cells of Lactococcus lactis by using flow cytometry.

  title={Detection of bacteriophage-infected cells of Lactococcus lactis by using flow cytometry.},
  author={Ole Michelsen and Alvaro Cuesta-Dom{\'i}nguez and Bjarne Albrechtsen and Peter Ruhdal Jensen},
  journal={Applied and environmental microbiology},
  volume={73 23},
Bacteriophage infection in dairy fermentation constitutes a serious problem worldwide. We have studied bacteriophage infection in Lactococcus lactis by using the flow cytometer. The first effect of the infection of the bacterium is a change from cells in chains toward single cells. We interpret this change as a consequence of a cease in cell growth, while the ongoing cell divisions leave the cells as single cells. Late in the infection cycle, cells with low-density cell walls appear, and these… CONTINUE READING
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