Detection of bacterial virulence genes associated with infective endocarditis in infected root canals.

@article{Bate2000DetectionOB,
  title={Detection of bacterial virulence genes associated with infective endocarditis in infected root canals.},
  author={A L Bate and J Ma and Thomas R Pitt Ford},
  journal={International endodontic journal},
  year={2000},
  volume={33 3},
  pages={
          194-203
        }
}
AIM The aim of this study was to examine whether bacteria associated with root canals possess genes that might predispose to bacterial colonization of the endocardium. METHODOLOGY Oligonucleotides were designed from DNA sequences encoding the functional binding regions of streptococcal fibronectin-binding protein (FnBP) and staphylococcal fibrinogen-binding protein (FgBP). The specificity and cross-reactivity of the oligonucleotide primers were investigated; streptococcal primers were tested… 

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