Detection of bacterial endosymbionts in clinical acanthamoeba isolates.

  title={Detection of bacterial endosymbionts in clinical acanthamoeba isolates.},
  author={Alfonso Iovieno and Dolena R. Ledee and Darlene M Miller and Eduardo C. Alfonso},
  volume={117 3},
  pages={445-52, 452.e1-3}
PURPOSE To determine the presence of 4 clinically relevant bacterial endosymbionts in Acanthamoeba isolates obtained from patients with Acanthamoeba keratitis (AK) and the possible contribution of endosymbionts to the pathogenesis of AK. DESIGN Experimental study. PARTICIPANTS Acanthamoeba isolates (N = 37) recovered from the cornea and contact lens paraphernalia of 23 patients with culture-proven AK and 1 environmental isolate. METHODS Acanthamoeba isolates were evaluated for the… CONTINUE READING