Detection of bacterial DNA in cardiac vegetations by PCR after the completion of antimicrobial treatment for endocarditis.

@article{Lang2004DetectionOB,
  title={Detection of bacterial DNA in cardiac vegetations by PCR after the completion of antimicrobial treatment for endocarditis.},
  author={Selwyn Lang and Richard W. Watkin and Peter A. Lambert and William A. Littler and Tom S. J. Elliott},
  journal={Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases},
  year={2004},
  volume={10 6},
  pages={579-81}
}
PCR with broad-range primers for prokaryotic 16S rRNA genes was used to identify bacterial DNA in tissue from patients undergoing valve replacements following a previous episode of infective endocarditis (IE). Of eight valves investigated, bacterial DNA was detected in three from patients for whom IE had been treated by antibiotic therapy 5, 12 and 18… CONTINUE READING